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Clinical Chemistry

Laboratory Experiments for Introduction to General, Organic and Biochemistry

Laboratory Experiments for Introduction to General, Organic and Biochemistry Lowest new price: $69.78
Lowest used price: $45.44
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Author: Frederick A. Bettelheim
Brand: Brooks / Cole

The 48 experiments in this well-conceived manual illustrate important concepts and principles in general, organic, and biochemistry. As in previous editions, three basic goals guided the development of all the experiments: (1) the experiments illustrate the concepts learned in the classroom; (2) the experiments are clearly and concisely written so that readers will easily understand the task at hand, will work with minimal supervision because the manual provides enough information on experimental procedures, and will be able to perform the experiments in a 2-1/2 hour laboratory period; and (3) the experiments are not only simple demonstrations, but also contain a sense of discovery. This edition includes many revised experiments and two new experiments.


  • Used Book in Good Condition

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Bioconjugate Techniques

Bioconjugate Techniques Lowest new price: $120.93
Lowest used price: $69.99
List price: $124.95
Author: Greg T. Hermanson

Bioconjugate Techniques, Third Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers.

  • Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab
  • Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates
  • Features full color illustrations
  • Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented

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Peptides: Synthesis, Structures, and Applications

Peptides: Synthesis, Structures, and Applications Lowest new price: $55.44
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In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries.

In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides.

  • The history of peptide chemistry
  • Amide formation, deprotection, and disulfide formation in peptide synthesis
  • Solid-phase peptide synthesis
  • a-helix formation by peptides in water
  • Stability and dynamics of peptide conformation
  • An overview of structure-function studies of peptide hormones
  • Neuropeptides:peptide and nonpeptide analogs
  • Reversible inhibitors of serine proteinases
  • Design of polypeptides
  • Current capabilities and future possibilities of soluble chemical combinatorial libraries
  • Epitope mapping with peptides
  • Synthesis and applications of branched peptides in immunological methods and vaccines

Drug Discovery for Leishmaniasis

Drug Discovery for Leishmaniasis Lowest new price: $170.42
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For human health, leishmaniasis is among the most important protozoan diseases, superseded only by malaria. Globally, 10 to 12 million people are infected with 1.5 million new cases every year. The development of cheaper new drugs is urgently needed for this neglected disease that is developing resistance to current treatments. Chemotherapy remains the only treatment option for the bulk of patients. However, this is largely unaffordable for most. In the past three years numerous advances in drug discovery have been made for treating this disease by exploiting diverging metabolic pathways between the Leishmania enzymes and their hosts, using nanotechnology to target the immune cell phagolysosomes where Leishmania resides.

Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania.

Recent studies have shown that leishmaniasis affects some of the poorest people in the world, with 95% of fatal cases occurring in only 6 countries. With the WHO goal of eliminating this public health problem in the South-east Asia Region by 2020, this book will be important for anyone who is interested in neglected tropical diseases.

Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols (Methods in Molecular Biology)

Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols (Methods in Molecular Biology) Lowest new price: $109.76
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This volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Chapters in the book cover a wide array of topics such as: quantitation of Flecainide, Mexiletine, Propafenone, and Amiodarone in Serum or Plasma; quantitation of total Buprenorphine and Norbuprenorphine in Meconium; quantitation or Carisoprodol and Meprobamate in Urine; and quantitation of Tricyclic Antidepressants in Serum. Each chapter contains a brief introduction to the topic, clinical utility of the analyte(s), and useful notes to help laboratorians easily reproduce the protocols discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and thorough, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, is a great resource for laboratorians who are already using mass spectrometry or thinking of introducing this technology to their laboratories.

Behavioral Neurobiology of Psychedelic Drugs (Current Topics in Behavioral Neurosciences)

Behavioral Neurobiology of Psychedelic Drugs (Current Topics in Behavioral Neurosciences) Lowest new price: $188.63
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This volume brings together the latest basic and clinical research examining the effects and underlying mechanisms of psychedelic drugs. Examples of drugs within this group include LSD, psilocybin, and mescaline. Despite their structural differences, these compounds produce remarkably similar experiences in humans and share a common mechanism of action.  Commonalities among the substances in this family are addressed both at the clinical and phenomenological level and at the basic neurobiological mechanism level. To the extent possible, contributions relate the clinical and preclinical findings to one another across species. The volume addresses both the risks associated with the use of these drugs and the potential medical benefits that might be associated with these and related compounds.

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Nutritional Biochemistry

Nutritional Biochemistry Lowest new price: $79.85
Lowest used price: $46.00
List price: $131.00
Author: Tom Brody
Brand: Brand: Academic Press

Nutritional Biochemistry takes a scientific approach to nutrition. It covers not just "whats"--nutritional requirements--but why they are required for human health, by describing their function at the cellular and molecular level. Each case study either leads to a subsequent discovery or enables an understanding of the physiological mechanisms of action of various nutrition-related processes. The text is "picture-oriented" and the commentary is directed towards explaining graphs, figures, and tables.

Nutritional Biochemistry includes a discussion of relevant aspects of physiology, food chemistry, toxicology, pediatrics, and public health. Experimental techniques for nutritional science are emphasized, and primary data is included to help give students a feel for the nutrition literature. This "real-world" approach provides students with a realistic view of the basis for much of our understanding of nutritional biochemistry.

  • Integrates biochemistry and nutrition in a case-oriented method
  • Emphasizes a hands-on approach to learning - case histories and clinical and research data illustrate all major points
  • Places emphasis on metabolism - metabolic pathways, enzymology, nutrient requirements (including RDA values)
  • Reveals the benefits of the Mediterranean diet, the biochemistry of exercise, the cell signaling pathways, how nutrition can influence the development of cancer, and the anthropometry and genetics of obesity


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Therapies for Retinal Degeneration: Targeting Common Processes

Therapies for Retinal Degeneration: Targeting Common Processes Lowest new price: $161.98
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Author: Thomas G Cotter (editor) Enrique J de la Rosa (editor)

Peptide-based Drug Discovery: Challenges and New Therapeutics

Peptide-based Drug Discovery: Challenges and New Therapeutics Lowest new price: $209.85
Lowest used price: $184.35
List price: $251.00

What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What are emerging therapeutics for peptide modalities? This book answers these questions with a holistic story from molecules to medicine, combining the themes of design, synthesis and clinical applications of peptide-based therapeutics and biomarkers. This book will be a valuable resource not only as a reference book for the researcher engaged in academic and pharmaceutical setting, but also a valuable resource to graduate students to understand discovery and development process for peptide-based medicine.

Organic Mechanisms

Organic Mechanisms Lowest new price: $62.00
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Author: Reinhard Brückner
Brand: Brand: Springer

“Much of life can be understood in rational terms if expressed in the language of chemistry. It is an international language, a language without dialects, a language for all time, a language that explains where we came from, what we are, and where the physical world will allow us to go. Chemical Language has great esthetic beauty and links the physical sciences to the b- logical sciences. ” from The Two Cultures: Chemistry and Biology by Arthur Kornberg (Nobel Prize in Physiology and Medicine, 1959) Over the past two centuries, chemistry has evolved from a relatively pure disciplinary pursuit to a position of central importance in the physical and life sciences. More generally, it has p- vided the language and methodology that has unified, integrated and, indeed, molecularized the sciences, shaping our understanding of the molecular world and in so doing the direction, development and destiny of scientific research. The “language of chemistry” referred to by my former Stanford colleague is made up of atoms and bonds and their interactions. It is a s- tem of knowledge that allows us to understand structure and events at a molecular level and increasingly to use that understanding to create new knowledge and beneficial change. The words on this page, for example, are detected by the eye in a series of events, now generally understood at the molecular level.


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