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|Annual Reports in Medicinal Chemistry, Volume 46
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Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.
|Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics
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Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring.
This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations.
- Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoring
- Focuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoring
- Explores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interference
- Explains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window
|The Laboratory Companion: A Practical Guide to Materials, Equipment, and Technique
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Author: Gary S. Coyne
Praise for The Laboratory Handbook by Gary S. Coyne
"This is probably the most useful volume I have encountered formany years and should be made compulsory reading for all thoseinvolved in research, particularly new research students."
"The book will be valuable for readers needing to understand thetheory and proper use, cleaning, and storing methods of laboratoryequipment. Safety issues are thoroughly covered. The book is auseful 'how-to-use' reference for students, novices, andexperienced laboratory personnel."
An updated version of the critically acclaimed Laboratory Handbook,this guide to laboratory materials, equipment, and techniques is animportant resource for students as well as veteran scientists andlab technicians.
From vacuum technology and glass vacuum systems to volumetricglassware, gas-oxygen torches, and cryogenic tanks, The LaboratoryCompanion provides complete coverage of all commonly used labequipment, including essential information about its selection,use, cleaning, and maintenance. It clearly explains the historicaldevelopment and rationale behind how and why things are done in thelab, and includes helpful guidelines and step-by-step proceduresfor each topic discussed.
Since glassware is typically the most prevalent type of labequipment, much of the book is devoted to the properties andhandling of glass apparatus, with additional material on rubber andplastic tubing, corks, stoppers, and O-rings. Readers will alsofind broad coverage of measurement systems, high- andlow-temperature apparatus and techniques, compressed gases, vacuumsystems, and other essential subjects.
|Chemistry (Quickstudy Reference Guides - Academic)
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Author: Inc. BarCharts
Brand: Brand: QuickStudy
Best-selling quick reference to chemistry. Chemistry essentials for students just beginning in chemistry or as an excellent reference throughout higher-level courses.
4-page laminated guide includes: • atomic structure • nuclear chemistry • atomic quantum numbers/orbitals • electronic atoms • types of matter/reactions • physical processes • nomenclature/stoichiometry • chemical interactions/bonding models • gases/thermodynamics/theories • and much more...
- *This is a laminated chart 8 x 5 inch on each side 4 sises.
- *Qty is one chart.
- *Quick Study Guide.
- *Contains different information in regards to chemistry.
|Perfumes, Cosmetics and Soaps: Volume II The Production, Manufacture and Application of Perfumes (POUCHER'S PERFUMES, COSMETICS, AND SOAPS)
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Author: W.A. Poucher
During the past decade there have been many changes in the perfumery industry which are not so much due to the discovery and application of new raw materials, but rather to the astronomic increase in the cost of labour required to produce them. This is reflected more particularly in the flower industry, where the cost of collecting the blossoms delivered to the factories has gone up year after year, so much so that most flowers with the possible exception of Mimosa, have reached a cost price which has compelled the perfumer to either reduce his purchases of absolutes and concretes, or alternatively to substitute them from a cheaper source, or even to discontinue their use. This development raises an important and almost insoluble problem for the perfumer, who is faced with the necessity of trying to keep unchanged the bouquet of his fragrances, and moreover, to ensure no loss of strength and diffusiveness. Of course, this problem applies more especially to the adjustment of formulae for established perfumes, because in every new creation the present high cost of raw materials receives imperative con sideration before the formula is approved.
|The Chemist's Companion: A Handbook of Practical Data, Techniques, and References
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Author: Arnold J. Gordon
Here in one source is a wide variety of practical, everydayinformation often required by chemists but seldom found together,if at all, in the standard handbooks, data collections, manuals,and other usual sources. Discussing physical, chemical, andmechanical properties of substances and systems, the authors answersuch questions as:
The book is divided into nine chapters and covers properties ofatoms and molecules, spectroscopy, photochemistry, chromatography,kinetics and thermodynamics, various experimental techniques, andmathematical and numerical information, including the definitions,values, and usage rules of the newly adopted International Systemof Units (SI Units). A section on statistical treatment of datawhich provides an actual least-squares computer program is alsoincluded. In the spectroscopy chapter, very extensive andup-to-date collections of spectral correlation data are presentedfor ir, uv-vis, optical rotation, nmr, and mass spectra, along withdata on esr and nqr spectroscopy. Also included is a variety ofhard-to-classify but frequently sought information, such as namesand addresses of microanalysis companies and chemistry publishers,descriptions and commercial sources of atomic and molecular models,and safety data for hazardous chemicals. More than 500 keyreferences are also included, most of which are recent. There areimportant hints and definitions associated with the art as well asthe state of the art for the appropriate subjects. Also foundthroughout the book are about 250 suppliers and directions forobtaining special booklets or other material.
- How do I test for and destroy peroxides in different solventsand what is the best way to purify such solvents?
- What are the structure, physical properties, and recentreferences to the use of common-name solvents and solvent aids suchas the "Skellysolves," "Cellosolves," "Crownanes," and"Glymes"?
- What is the utility of a particular molecular sieve, orpermeation gel, or epoxy cement, or liquid crystal, and where do Ibuy them and find references to their application?
Containing a wealth of useful information, The Chemist'sCompanion will be an indispensable guide for students andprofessional chemists in nearly all the chemical disciplines. Inaddition, it will provide for the teacher and student an unusualadjunct for use in a broad cross-section of chemistry courses.
|Contract Research and Development Organizations: Their Role in Global Product Development
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Author: Shayne C. Gad
The last 10 years have seen a seismic shift in therapeutic product development and testing. In both the pharmaceutical (both small and large molecule) and medical device sectors, the vast majority of testing and evaluation of products is not performed within innovator companies, but rather has been outsourced to a growing universe of commercial organizations. The authors both have more than 30 years experience in this field, and both have worked within innovator companies, for CROs, and as consultants in the field. Contract Research and Development Organizations: Their Role in Global Product Development has been crafted by these authors to provide a how to guide for all aspects of working with CROs in selecting, working with and ensuring the best possible desirable outcome of having the R&D function, or substantial parts of it, outsourced. It uses as the exemplary case nonclinical safety assessment, biocompatibility and efficacy testing which are to be performed to select the best possible candidate compound, device or formulation and then moving the resulting regulated therapeutic medical product into and through the development process and to marketing approval. But also covered are the contract synthesis of drug substances and corresponding manufacture of biologics and manufacture of products, formulation development, clinical evaluation, regulatory and document preparation support, and use of consultants.
Included in the volume are an exhaustive listing of those CROs in the (drug and device) safety evaluation sector and their contact information and capabilities, and extensive similar listing for the other types of contract service providers. Also included are guidances on how to monitor ongoing work at contract facilities and audit check lists for GLP, GMP and GCP facilities. These listings are international in scope, and a specific chapter addresses working with some of the newer international CROs.
|Pharmaceutical Formulation: The Science and Technology of Dosage Forms (Drug Discovery)
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Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field.
Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development.
Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.
|Chromatography for Sustainable Polymeric Materials: Renewable, Degradable and Recyclable (Advances in Polymer Science)
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With the highest impact factor of all publications ranked by ISI within Polymer Science, this collection of short and concise reports on the physics and chemistry of polymers, each written by world-renowned experts, is still valid and useful after 10 years.
|Chemical Magic (Dover Books on Chemistry)
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Author: Leonard A. Ford
Classic guide provides intriguing entertainment while elucidating sound scientific principles, with more than 100 unusual stunts: cold fire, dust explosions, a nylon rope trick, a disappearing beaker, much more.
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