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Hematology


Blood Stem Cell Transplantation (Cancer Treatment and Research)

Blood Stem Cell Transplantation (Cancer Treatment and Research) Lowest new price: $494.34
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Brand: Brand: Springer

Blood Stem Cell Transplantation conveys the excitement that accompanies the newest developments in hematopoietic stem cell transplantation. Some of the applications that stand to impact this field most significantly are based on recent advances in the biological sciences, as demonstrated by the chapters on gene therapy, on the detection of minimal residual disease using molecular techniques, and on the use of radioimmunoconjugates targeting lymphoma and leukemia-associated antigens. Others are the results of clinical observations - e.g., the association between graft-versus-host- disease (GVHD) and durable remissions that have led to creative clinical experiments such as donor leukocyte infusions (DLI). Attempts to unravel the biological events that underlie the responses seen in patients with relapsed chronic myelogenous leukemia treated with DLI are likely to provide the basis for future refinements in this clinical approach. Hopefully, improved response rates and reduced toxicity will result. The power of the immunologic response in controlling malignant disease is underscored in the chapter on post-transplant immunotherapy. The complex immunologic process that results in clinical GVHD may be dissected and engineered to provide clinical benefits that include, in addition to its antineoplastic effects, the amelioration of its clinical manifestations. Better control of GVHD with less global immunosuppression will facilitate the use of mismatched and unrelated donors. This area of investigation perfectly illustrates the continued interplay between the laboratory and the clinic. The continued cross-fertilization of ideas between immunologists, molecular biologists and clinical investigators is likely to yield important advances in this field for years to come.
Possible applications of stem cell transplantation continue to grow with the identification of alternative sources of stem cells and the potential to engineer and/or expand the graft. Although the use of unrelated and mismatched donors continues to increase, the possibilities associated with umbilical cord blood transplantation are legion, especially if stem cells can be expanded ex vivo to provide grafts for full-sized adults. Using techniques in which contaminating malignant cells may be eliminated from autografts through positive selection, autologous transplantation may prove highly effective, especially when coupled with post-transplant immunotherapy. Some of these same methodologies have helped facilitate the use of autologous grafts for transplantation in patients with chronic myelogenous leukemia without allogeneic donors.
Advances in the supportive care of transplant patients, including the pretransplant identification of those at risk from pulmonary complications and the use of cytokines to speed engraftment, have reduced morbidity and mortality to such a degree that it is appropriate to consider high-dose therapy and stem cell reconstitution in patients with nonmalignant diseases. The impressive advances that have occurred in transplantation for thalassemia are described by pioneers in their area of investigation. The burgeoning field of transplantation for autoimmune disorders, including its immunobiologic basis and soon-to- be-realized clinical potential, is also summarized. Continued progress in the use of high-dose therapy with stem cell rescue for the treatment of pediatric tumors, which derives in part from improved supportive care, is detailed.
The sobering voice of the health care economists underscores the necessary limitations to our seemingly unbridled imagination. Cost- consciousness and financial know-how will need to be reflected in future study designs. Given the seemingly endless applications of our technology, strategies to insure its cost-effectiveness will be necessary. Continued financial support for laboratory investigation and for the clinical experiments they generate will be required if we are to go forward. Blood Stem Cell Transplantation lays the foundation for many of these future advances; it is incumbent upon us all to insure its realization.

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A Homoeopathic Approach to Cancer

A Homoeopathic Approach to Cancer Lowest new price: $42.90
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Author: A. U. Ramakrishnan

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Dx/Rx: Lymphoma (Dx/Rx Oncology Series)

Dx/Rx: Lymphoma (Dx/Rx Oncology Series) Lowest new price: $38.29
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Author: Daniel O. Persky

Tightly organized into a super-condensed, outline-bulleted format, this handy, pocket-sized manual details precise, up-to-date information for diagnosis and treatment of lymphoma. Comprehensive and concise, the book covers epidemiology and guidelines for diagnosis and surgical, radiotherapeutic and chemotherapeutic treatment options. Throughout the handbook, tables and figures summarize important clinical data and current professional society recommendations, while salient references direct readers to additional information. Current, quick, and concise, for instant access on the ward or in the clinic!


Coagulation and Flocculation: Theory and Applications (Surfactant Science)

Coagulation and Flocculation: Theory and Applications (Surfactant Science) Lowest new price: $130.25
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Brand: Brand: CRC Press

This volume details the thermodynamics and kinetics of the adsorption of surfactants and polymers on solids, as well as coagulation and flocculation mechanisms - demonstrating the applicability of the newest theoretical approaches on practical systems.;Written by over 15 international experts in the field, Coagulation and Flocculation: treats the Gouy-Chapman theory of an isolated planar charged surface and the DLVO theory describing the interaction between two identical charged surfaces; shows which energies are responsible for structure formation, what types of structure can be built in diluted and concentrated systems and how such structures can be studied and characterized; describes the interplay between interface and hydrodynamic forces and derives equations for calculating their individual probabilities; examines the use of microscopy, photography, individual particle sensors, sedimentation and light scattering to measure aggregate size distributions; and discusses methods for forming ceramics and the effects of improvements in powder packing and the stabilization of powder suspensions on processing steps.

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Human Eosinophils: Biological and Clinical Aspects (Chemical Immunology and Allergy, Vol. 76)

Human Eosinophils: Biological and Clinical Aspects (Chemical Immunology and Allergy, Vol. 76) Lowest used price: $27.41
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Eosinophils represent approximately 1% of peripheral blood leukocytes and play a central proinflammatory and immunoregulatory role in various immune disorders. This volume provides the reader with a comprehensive survey of the major aspects of human eosinophilic biology and immunology as well as the most clinically relevant aspects of eosinophil-related disorders. Expert contributions cover the ultrastructural and phenotypic characteristics of human eosinophils, and their fundamental biochemical features including receptors for IgE and chemokines. The production of cytokines and their role in the activation of eosinophils are reviewed. Furthermore, the classic eosinophil-related disorders such as hypereosinophilia, drug reactions, allergic disorders and some cardiovascular diseases are described. Each of the chapters is written by an investigator actively engaged in research on the topic under consideration. The well-edited and stimulating material compiled in this volume will be of interest to all those working in allergology, immunology, biochemistry and pulmonary medicine.


Technical Manual of American Association of Blood Banks

Technical Manual of American Association of Blood Banks Lowest new price: $49.99
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Author: Vengelen-tyler
Brand: Brand: Amer Assn of Blood Banks

The 14th edition examines theoritical and clinical materials, as well as technical details.

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Atlas of Atherosclerosis and Metabolic Syndrome

Atlas of Atherosclerosis and Metabolic Syndrome Lowest new price: $40.70
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Brand: Brand: Current Medicine Group

This new edition is an integral source of information on Atherosclerosis. It covers topics such as newer coronary risk factors, high-density lipoprotein metabolism, lipid-lowering drugs, endothelium and thrombosis in atherogenesis, and contributing risk factors. With over 500 exceptional photographs, diagrams, and charts, each chapter illustrates an important facet of diagnosing and treating this common and often fatal disease.

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Carbon Dioxide Equilibria and Their Applications

Carbon Dioxide Equilibria and Their Applications Lowest new price: $146.03
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Author: James N. Butler
Brand: CRC Press

Carbon dioxide, bicarbonate ion, and carbonate ion comprise the most important acid-base system in natural waters, and the equilibria between them regulate the pH of seawater, as well as most rainwater, stream water, river water, and groundwater. Carbon Dioxide Equilibria and Their Applications provides a clear, compact presentation of this topic, which is central to geochemistry and environmental engineering. It emphasizes a rigorous mathematical and thermodynamic basis for calculations and their application to realistic problems.

The book's first four chapters present the basic equations, mathematical techniques for visualizing and manipulating them, and data on equilibrium constants and activity coefficients. These are presented in the general context of acid-base titration and solubility of CaCO3. The remaining chapters show how these concepts and techniques are applied to geochemistry and oceanography, in addition to their applications to water conditioning. Specific topics discussed include acid rain, freshwater, seawater, carbonate sediments in the deep oceans, the effects of increased atmospheric CO2 on the oceans, estuarine waters, brines, hydrothermal solutions, pH adjustment, prediction of calcium carbonate saturation, corrosion inhibition, and water softening.

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Oxygen Transport to Tissue XXI (Advances in Experimental Medicine and Biology) (v. 21)

Oxygen Transport to Tissue XXI (Advances in Experimental Medicine and Biology) (v. 21) Lowest new price: $42.44
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The International Society on Oxygen Transport to Tissue (lSOTT) held its 26th annual meeting from August 23-26, 1998, and met for the second time in Budapest. As captured in the design of the ISOTT'98 logo, the venue of the conference was the Budapest Hilton in the heart of the historic Castle District in Buda, across from Hungary's coronation church-the Matthias Church-and the fairy-tale-like Fisherman's Bastion; a special place with a historical touch situated atop the Castle Hill, from where participants enjoyed the spectacular panoramic views of Budapest exquisitely laid out on both sides of the Danube. In preparation for ISOTT'98, major emphasis was given to the application of informatics in collecting, presenting, and disseminating scientific and other information associated with the meeting. Electronic submission of the abstracts made it possible to publish the illustrated Abstracts on the ISOTT'98 Web Site well before the meeting. Following the meeting, an ISOTT'98 CD was published as a digital, searchable record of ISOTT'98. The scientific program was designed with the active participation of prospective attendees, in that priority and momentum was given to the topics selected by those visiting the Web Site. Poster and oral presentations were considered as equivalently effective formats, reflected by the fact that posters were on display throughout the meeting.


Preventing Infectious Disease

Preventing Infectious Disease Lowest new price: $88.78
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Brand: Brand: Jones Bartlett Publishers

Intended for blood bank employees and other health care workers, this slim training manual explains OSHA guidelines for minimizing exposure to bloodborne pathogens through a combination of universal precautions, work practice controls, engineering controls, and personal protective equipment. It also describes the symptoms, diagnosis, and treatment of 15 common infectious diseases. Previously published as Bloodborne pathogens, 4th ed. in 2001. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com)

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