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Hematology


A Homoeopathic Approach to Cancer

A Homoeopathic Approach to Cancer Lowest new price: $42.90
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Author: A. U. Ramakrishnan

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Prognostic Markers in Hematologic Oncology

Prognostic Markers in Hematologic Oncology Lowest new price: $50.84
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Author: Wojciech Gorczyca

Effective treatment of the tumors of the hematopoietic system now often depends on an exact prognosis for the disorder concerned, and so the hematopathologist can give vital direction to the hematologic or oncologic clinician. Prognostic Markers in Hematologic Oncology comprehensively presents the numerous predictive and prognostic parameters in the practice of oncologic haematology and underlines their clinical relevance.


Circulating Nucleic Acids in Plasma and Serum IV, Volume 1075 (Annals of the New York Academy of Sciences) (v. 4)

Circulating Nucleic Acids in Plasma and Serum IV, Volume 1075 (Annals of the New York Academy of Sciences) (v. 4) Lowest new price: $39.99
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Brand: Brand: Wiley-Blackwell

An accurate, inexpensive, and noninvasive method for the early diagnosis of cancer has been something of a holy grail among cancer researchers, but until recently a method meeting all three criteria has been elusive. Nucleic acids were first discovered in circulation in 1948, but it was not until the 1960s and 70s that patients with autoimmune disease and cancer were discovered to have higher levels of circulating DNA than were detected in in healthy persons.

The focus in this volume is on three major applications of the circulating nucleic acids detection method: cancer, fetal medicine, and diseases such as diabetes, stroke, and myocardial infarction. In addition, there are reports on the biology and origins of circulating DNA and RNA and on improved methods for the detection of nucleic acids in plasma and serum.

The circulating DNA found in cancer patients has many characteristics in common with their tumors, which made it an attractive candidate for use in the diagnosis and management of patients with malignancies. This method can also be applied to the assessment of the sublinical tumor burden in cancer patients, thus reducing the risk of unnecessary chemotherapy.

Detection of nucleic acids circulating in maternal serum means that fetal diagnosis may be possible without resorting to the more dangerous and invasive methods now used (e.g., amniotic fluid and chorionic villus sampling). Detection of problems in the pregnancy such as preeclampsia and intrauterine growth retardation may also become possible through maternal blood samples.

In diabetic patients, circulating nucleic acids can be used for the early detection of developments such as retinopathy.

The benefits of using circulating nucleic acids in the diagnosis and management of cancer and chronic disease will be realized through earlier detection by means of this less expensive and less invasive testing technique and through its potential for closer monitoring of the disease.

NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.

ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member

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Principles of Molecular Oncology

Principles of Molecular Oncology Lowest new price: $40.00
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Brand: Brand: Humana Press

This complete updating and expansion of a highly praised survey of the molecular basis of cancer reflects emerging knowledge coming from genomics, proteomics, chemoprevention strategies, new molecular targets, therapeutic monoclonal antibodies, and innovative cytotoxic and cytostatic small molecular weight compounds. New topics of special interest include the combining of molecular diagnostics (expression profiling of genes and proteins) with developmental therapeutics and the "binary state" concept (active/inactive) that seeks more relevant targets within the global molecular matrix of a given cancer. The book looks forward to new strategies that will not just attempt to "kill" cancer cells and "cure" cancers forever, but to hit those molecular targets to reduce the proliferative advantage of cancer cells and abolish or diminish their metastatic properties.

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Atlas of Atherosclerosis and Metabolic Syndrome

Atlas of Atherosclerosis and Metabolic Syndrome Lowest new price: $44.90
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Brand: Brand: Current Medicine Group

This new edition is an integral source of information on Atherosclerosis. It covers topics such as newer coronary risk factors, high-density lipoprotein metabolism, lipid-lowering drugs, endothelium and thrombosis in atherogenesis, and contributing risk factors. With over 500 exceptional photographs, diagrams, and charts, each chapter illustrates an important facet of diagnosing and treating this common and often fatal disease.

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Venous Thrombosis: From Genes to Clinical Medicine (Human Molecular Genetics)

Venous Thrombosis: From Genes to Clinical Medicine (Human Molecular Genetics) Lowest new price: $16.97
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Author: D.N. Cooper and M. Krawczak
Brand: Brand: Garland Science

Thrombotic disease is a major cause of death and disablement in Western society. Venous Thrombosis: from genes to clinical medicine presents our current knowledge of potentially prothrombotic protein abnormalities, together with clear and concise views of

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Mechanisms in Blood Coagulation, Fibrinolysis and the Complement System

Mechanisms in Blood Coagulation, Fibrinolysis and the Complement System Lowest new price: $70.39
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Author: Torben Halkier

Blood coagulation and fibrinolysis has been traditionally classed as a part of hematology and the complement system as a part of immunology. An analysis of these two systems at a molecular level, however, has revealed some intriguing evolutionary relationships among some of the macromolecules involved. Evidently, there are similarities in the cascade of reactions that characterize the processes. It is therefore highly suitable that these topics are presented together in one volume. This book presents a thorough explanation and analysis of our current understanding of the proteins and enzymes involved in each of the three processes, and includes a section devoted to special topics of relevance, such as the kinin system, glycosylation, signal peptides, and the serpin family.


New Therapeutic Agents In Thrombosis And Thrombolysis, Revised And Expanded, Second Edition (Fundamental and Clinical Cardiology)

New Therapeutic Agents In Thrombosis And Thrombolysis, Revised And Expanded, Second Edition (Fundamental and Clinical Cardiology) Lowest new price: $34.92
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Brand: Brand: CRC Press

Presents new chapters discussing the latest research on low-molecular-weight heparins, as well as agents such as pentasaccharide, TFP1, soluble thrombomodulin, and alfimeprase.

Completely revised and expanded throughout, New Therapeutic Agents in Thrombosis and Thrombolysis details strategies to

  • target conventional and recently characterized pathways of hemostasis
  • minimize the prothrombotic function of activated platelets
  • assess the biochemical and pharmacological effects of antithrombotic agents
    and discusses
  • the use of animal models for determination of antithrombotic drug efficacy
  • antithrombotic therapy as a key component of cardiovascular disease management
  • the management of thromboembolic events in children and pregnant women
    Supplemented with more than 2000 contemporary references, New Therapeutic Agents in Thrombosis and Thrombolysis is an authoritative source for cardiologists, internists, primary care physicians, vascular medicine specialists, cardiovascular and vascular surgeons, hematologists, pulmonologists, critical care physicians, pharmacologists, pharmaceutical researchers, and fellows, residents, and graduate and medical school students in these disciplines.
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    Molecular Biology of B-Cell and T-Cell Development (Contemporary Immunology)

    Molecular Biology of B-Cell and T-Cell Development (Contemporary Immunology) Lowest new price: $33.00
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    Brand: Brand: Humana Press

    Despite the tremendous diversity of the cells of the hematopoietic system, they are all derived from common precursor cells that are generated in the fetus and persist into adult life. In this regard, Band T lymphocytes, which comprise the two arms of the antigen-specific and inducible immune system, though functionally very different, are descendants of the same stem cell precursor. In the past several years, we have witnessed an explosion of information regarding the process by which differentiation of B-and T-cells from stem cells occurs. This information, like the answers to most important biological questions, has come from multiple and diverse directions. Because all hematopoietic cells arise from common precursors, complex regulatory processes must be involved in determining commitment to various lineages. Understanding commitment to the B- or T-cell lineage remains incomplete; however, identification of transcription factors necessary for progression along specific B-and T-cell pathways suggests that we are on the verge of understanding the molecules involved in the initial fate-determining steps. Studies of this type previously could be accomplished only in nonmammalian systems that are more amenable to genetic approaches. However, new technologies allow increasingly elegant and informative studies in mammalian systems, particularly for cells of the hematopoietic system.

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    Bloodborne Pathogens (American College of Emergency Physicians)

    Bloodborne Pathogens (American College of Emergency Physicians) Lowest new price: $12.53
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    Author: American Academy of Orthopaedic Surgeons (AAOS)
    Brand: Brand: Jones n Bartlett Learning

    Over five million workers in health care related fields are at risk of exposure to bloodborne pathogens, such as the HIV virus and hepatitis B virus. Designed to meet the current OSHA training requirements, Bloodborne Pathogens was created for students and employees who have potential for occupational exposure to blood or other potentially infectious materials, and even has supplemental information on airborne pathogens such as tuberculosis. The Fifth Edition has been completely revised and updated to comply with the 2005 guidelines for cardiovascular resuscitation (CPR) and emergency cardiovascular care (ECC).

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