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Bujold, Lois McMaster
Card, Orson Scott
Chalker, Jack L.
Heinlein, Robert A.
McKillip, Patricia A.
Nye, Jody Lynn
|Organic Stereochemistry: Guiding Principles and Biomedicinal Relevance
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"This book should become an indispensable asset on the bookshelves of pharmaceutical laboratories in academia and in industry, as well as of laboratories devoted to plant protection. I am convinced that studying this book will be an eye-opener for many scientists in the field of life sciences. Furthermore, for teachers in this area it will not only be a useful compilation of the various languages and definitions of organic stereochemistry, but also a welcome source of examples for demonstrating to their students the intricate and intriguing role stereochemistry plays in the chemistry of life." - Prof. Dr. Dieter Seebach, Laboratory of Organic Chemistry, ETH Zurich, Switzerland
This textbook presents the molecular scale of matter in the broad diversity and richness of its three dimensions, giving due attention when relevant to the temporal dimension in which molecules exist, act, and react.
The focus is on two significant fields of three-dimensional chemistry: a presentation of the guiding principles in organic stereochemistry, followed by a focus on the biochemical and medicinal relevance of this discipline.
The treatment of Guiding Principles gives priority to didactic clarity and nomenclature issues, as detailed and illustrated in Parts 1 to 4:
'Symmetry Elements and Operations, Classification of Stereoisomers'
'Stereoisomerism Resulting from One or Several Stereogenic Centers'
'Other Stereogenic Elements: Axes of Chirality, Planes of Chirality, Helicity, and (E,Z)-Diastereoisomerism'
'Isomerisms about Single Bonds and in Cyclic Systems'
This is followed by Parts 5 to 8 which focus on the biomedicinal relevance of stereochemistry, with special reference to the biochemistry and pharmacology of medicinal compounds.
Here, examples and applications are discussed and illustrated based on their relevance to a given specific stereochemical aspect:
'Chirality in Molecular and Clinical Pharmacology'
'The Conformational Factor in Molecular Pharmacology'
'The Concept of Substrate Stereoselectivity in Biochemistry and Xenobiotic Metabolism'
'Prostereoisomerism and the Concept of Product Stereoselectivity in Xenobiotic Metabolism'
Finally, the book contains a gift for broad-minded readers with an interest in the historical roots of stereochemistry:
'Molecular Chirality in Chemistry and Biology: Historical Milestones'
* Consists entirely of beautifully produced colored figures
* Includes marginal notes, giving clear-cut short definitions of terms used in the corresponding caption
* Provides an alphabetic glossary of terms
* Offers an extensive index
|Stereochemistry and Stereoselective Synthesis: An Introduction
Lowest new price: $56.07
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Author: Mihály Nógrádi
Written by a well-respected and experienced author, this textbook fills the gap for a concise introduction to the key concepts of organic stereochemistry and the most important classical and modern methods in stereoselective synthesis.
The concepts are extensively illustrated in color, with practical examples and question-answer sets to help consolidate the reader's knowledge. In addition, animations are available from the Wiley website.
A must-have for students in chemistry, biochemistry, and life sciences, as well as researchers in pharmaceutical and agrochemical companies in need of a quick introduction to the field.
|The CH-Pi Interaction: Evidence, Nature, and Consequences
Lowest new price: $65.54
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Author: Motohiro Nishio
A systematic exploration of the fascinating area of CH/pinteraction-from the frontier of chemical research
The CH/p bond may be the weakest of the hydrogen bonds, but it hasbeen found to play important roles in the physical, chemical, andbiological properties of a variety of substances. This book offersa complete overview of the experimental basis, theoreticalbackground, and nature of the CH/p interaction to facilitate aclearer common understanding of the interaction between CH bondsand p-systems. Featured topics include:
* Evidence and methods of detection
* Quantum chemical treatment of CH/p interaction
* Comparison with other types of weak molecular interactions
* Conformational consequences
* Chiroptical properties
* Selectivity in organic reactions
* Crystal structures of clathrates
* Inclusion compounds
* Interligand interactions in coordination chemistry
* Specific interactions in protein structures
* Prospects and possibilities for use in biochemistry and materialsscience
The CH/p Interaction makes an important contribution to theunderstanding of weak intermolecular forces and their potentialvalue to the biochemical and pharmaceutical sciences. It will bewelcomed by physical and synthetic organic chemists; structuralchemists; and pharmaceutical and biochemists.
|Materials for Nonlinear Optics: Chemical Perspectives (ACS Symposium Series)
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Brand: Brand: American Chemical Society
This volume exposes the chemistry community to the critical role that chemistry can and must play in nonlinear optics research. In addition, it brings together those researchers who synthesize and characterize materials from a variety of systems, with those who build devices, giving chemists, physicists, and engineers a greater appreciation for the opportunities that lie ahead in understanding and developing nonlinear optical materials. The volume begins with a discussion of polarizability and hyperpolarizability from the view of a chemist. Tutorial chapters dealing with the fundamental structures and properties of second- and third-order nonlinear optical materials, measurement and characterization of these systems, theoretical considerations, application of these systems to devices, and overviews of the current state of affairs in both organic and inorganic nonlinear optical materials follow.
- Used Book in Good Condition
|Applications of Nmr Spectroscopy to Problems in Stereochemistry and Conformational Analysis (Methods in Stereochemical Analysis)
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|Stereoelectronic Effects in Organic Chemistry (Organic chemistry series)
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Author: Pierre Deslongchamps
|The Nuclear Overhauser Effect in Structural and Conformational Analysis, 2nd Edition
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List price: $279.00
Author: David Neuhaus
An authoritative review of the state of the art in the NuclearOverhauser Effect-essential information for organic chemists,biochemists, biophysicists, and NMR spectroscopists
The field of NMR spectroscopy has seen tremendous growth in thelast twenty years, particularly advances relating to NuclearOverhauser Effect (NOE) spectroscopy-the most powerful techniquefor obtaining structural information on molecules in solution.Extensive and engaging, the Second Edition of the leading referenceon the NOE is significantly updated to reflect the latest changesand new approaches in the field.
Neuhaus and Williamson provide an essential guide to thecomplexities and use of the NOE in a readily accessible,straightforward manner. Their practical handbook features a newchapter addressing the use of NOE data to calculate biomolecularstructures. Chapters dealing with the kinetics of the NOE, theeffects of exchange and internal motion, and applications of theNOE, are also extensively revised. Cross-referenced in remarkabledepth, The Nuclear Overhauser Effect is organized into three mainparts:
* Part I describes the theory of the Nuclear Overhauser Effect in aclear, comprehensive fashion
* Part II discusses the considerations involved in implementing NOEexperiments, including full coverage of all necessary details forboth new and established techniques
* Part III offers examples of how the NOE is used, includingapplications to defining molecular geometry, stereochemistry,conformation, and biomolecular structure and interactions
The Nuclear Overhauser Effect in Structural and ConformationalAnalysis, Second Edition, uniquely explains the NOE in detail,making it an indispensable resource for the novice as well as theexperienced NMR researcher.
|Organic Conformational Analysis and Stereochemistry from Circular Dichroism
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Author: David A. Lightner
A unique guide to variable temperature CD spectroscopy and itsapplication in organic chemistry
This timely, original, thought-provoking work looks at organicstereochemistry from the perspective of circular dichroism (CD),using variable temperature CD spectroscopy to determine theconformation or absolute configuration of chiral molecules. With anemphasis on the analysis of optically active ketones and thecarbonyl chromophore, the authors demonstrate the advantages ofthis highly sensitive spectroscopic tool for obtainingstereochemical information in diverse areas of organic chemistry,biochemistry, and medicinal/pharmaceutical chemistry. They combinedetailed examples of stereochemical analysis with clear, thoroughpresentations, correlating chiroptical data with molecularmechanics calculations as well as data from NMR spectroscopy andother spectroscopic techniques. In addition, they provide asystematic survey of the professional literature, featuring anextraordinary collection of original CD spectra run at varyingtemperatures. Coverage includes:
* Chiroptical measurements: CD and ORD (Optical RotatoryDispersion)
* Conformational analysis of compounds ranging from simple cyclicketones to polycyclics
* Conjugated and homoconjugated systems
* Stereochemistry of the carbon-carbon double bond
* Stereochemistry from exciton coupling of two or morechromophores
* An interesting historical account of the development ofstereochemical concepts
|Carbon-Carbon and Carbon-Proton Nmr Couplings: Applications to Organic Stereochemistry and Conformational Analysis (Methods in Stereochemical Analysis)
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Author: James L. Marshall
Brand: Brand: Vch Pub
Book by Marshall, James L.
- Used Book in Good Condition
|Circular Dichroic Spectroscopy: Exciting Coupling in Organic Stereochemistry
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Author: Koji Nakanishi
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