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|Physical Biology: From Atoms to Medicine
Lowest new price: $41.08
Lowest used price: $37.09
List price: $48.00
Author: Ahmed Zewail
Brand: Ahmed H Zewail
Edited by Nobel Laureate, Ahmed Zewail, this pioneering book on physical biology includes contributions from four Nobel laureates and other eminent scientists.
This book brings about the confluence of various concepts and tools to address significant problems of our time in physical biology and adjacent disciplines. The volume is structured to provide a broad perspective on current state-of-the-art methods and concepts at the heart of chemical and biological behavior, covering the topics of visualization; theory and computation for complexity; macromolecular function, protein folding, and protein misfolding; molecular recognition; and systems integration from cells to consciousness. The scope of tools is wide-ranging, spanning imaging, crystallography, microfluidics, single-molecule spectroscopy, and synthetic probe targeting, either molecular or by metallic particles. The perspectives are from the point of view of world leaders in physics, chemistry, and biology; and they define potential new frontiers at the interface of these disciplines, including physical, systems, and synthetic biology.
Contents: The Preoccupations of 21st-Century Biology (D Baltimore); Physical Biology: 4D Visualization of Complexity (A H Zewail); The Challenge of Quasi-Regular Structures in Biology (R D Kornberg); The Future of Biological X-ray Analysis (D C Rees); Biology by the Numbers (R Phillips); The Neurobiology of Consciousness (C Koch & F Mormann); Precision Measurements in Biology (S R Quake); Symmetry Breaking, Delocalization and Dynamics in Electron Transfer Systems (N S Hush); and other papers.
- Physical Biology From Atoms to Medicine
|Cell Biology: With STUDENT CONSULT Access, 2e (Pollard, Cell Biology, with Student Consult Online Access)
Lowest new price: $89.83
Lowest used price: $11.99
List price: $124.00
Author: Thomas D. Pollard MD
A masterful introduction to the cell biology that you need to know! This critically acclaimed text offers you a modern and unique approach to the study of cell biology. It emphasises that cellular structure, function, and dysfunction ultimately result from specific macromolecular interactions. You'll progress from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states. The outstanding artwork helps you to better visualise molecular structures.
- Covers essential concepts in a more efficient, reader-friendly manner than most other texts on this subject.
- Makes cell biology easier to understand by demonstrating how cellular structure, function, and dysfunction result from specific macromole¬cular interactions.
- Progresses logically from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states.
- Helps you to visualize molecular structures and functions with over 1500 remarkable full-color illustrations that present physical structures to scale.
- Explains how molecular and cellular structures evolved in different organisms.
- Shows how molecular changes lead to the development of diseases through numerous Clinical Examples throughout.
- Includes STUDENT CONSULT access at no additional charge, enabling you to consult the textbook online, anywhere you go · perform quick searches · add your own notes and bookmarks · follow Integration Links to related bonus content from other STUDENT CONSULT titles―to help you see the connections between diverse disciplines · test your knowledge with multiple-choice review questions · and more!
- New keystone chapter on the origin and evolution of life on earth probably the best explanation of evolution for cell biologists available!
- Spectacular new artwork by gifted artist Graham Johnson of the Scripps Research Institute in San Diego. 200 new and 500 revised figures bring his keen insight to Cell Biology illustration and further aid the reader’s understanding.
- New chapters and sections on the most dynamic areas of cell biology - Organelles and membrane traffic by Jennifer Lippincott-Schwartz; RNA processing (including RNAi) by David Tollervey., updates on stem cells and DNA Repair.
- ,More readable than ever. Improved organization and an accessible new design increase the focus on understanding concepts and mechanisms.
- New guide to figures featuring specific organisms and specialized cells paired with a list of all of the figures showing these organisms. Permits easy review of cellular and molecular mechanisms.
- New glossary with one-stop definitions of over 1000 of the most important terms in cell biology.
- Used Book in Good Condition
|Protein Structure and Function
Lowest new price: $63.17
Lowest used price: $33.55
List price: $79.95
Author: Gregory A. Petsko
Brand: Brand: Sinauer Associates, Inc.
Published by New Science Press and distributed in the U.S. and Canada by Oxford University Press
This text introduces general principles of protein structure, folding, and function, then goes beyond these basics to tackle the conceptual basis of inferring structure and function from genomic sequence. It is the first book in a series, Primers in Biology, employing a modular design in which chapters are divided into topics, each occupying one two-page spread that includes the relevant text, illustrations (in full color), definitions, and references.
The book has five chapters. The first is an introduction to the principles of protein structure and folding, with emphasis on proteins' biophysical properties. The second describes the principles of the main biochemical functions of proteins, namely binding and catalysis, with a short section on the properties of structural proteins. Chapter 3 covers the regulation of protein function, containing concise descriptions of all the regulatory mechanisms that operate on proteins, from pH to phosphorylation, with several sections on protein switches based on nucleotide hydrolysis. Chapter 4 introduces the principles whereby structure and function are deduced from sequence, with illustrative examples. The final chapter addresses how data on protein structure is gathered, interpreted, and presented.
Written for upper-level undergraduates and beginning graduate students, Protein Structure and Function is also be for working scientists needing an up-to-date introduction to the field.
- Used Book in Good Condition
|Molecular Cytogenetics: Protocols and Applications (Methods in Molecular Biology, Vol. 204)
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Brand: Yao Shan Fan
The new techniques of molecular cytogenetics, mainly fluorescence in situ hybridization (FISH) of DNA probes to metaphase chromosomes or interphase nuclei, have been developed in the past two decades. Many FISH techniques have been implemented for diagnostic services, whereas some others are mainly used for investigational purposes. Several hundreds of FISH probes and hybridization kits are now commercially available, and the list is growing rapidly. FISH has been widely used as a powerful diagnostic tool in many areas of medicine including pediatrics, medical genetics, maternal–fetal medicine, reproductive medicine, pathology, hematology, and oncology. Frequently, a physician may be puzzled by the variety of FISH techniques and wonder what test to order. It is not uncommon that a sample is referred to a laboratory for FISH without indicating a specific test. On the other hand, a cytogeneticist or a technologist in a laboratory needs, from case to case, to determine which procedure to perform and which probe to use for an informative result. To obtain the best results, one must use the right DNA probes and have reliable protocols and measures of quality assurance in place. Also, one must have sufficient knowledge in both traditional and molecular cytogenetics, as well as the particular areas of medicine for which the test is used in order to appropriately interpret the FISH results, and to correlate them with clinical diagnosis, treatment, and prognosis.
- Molecular Cytogenetics Protocols and Applications
|Triple Repeat Diseases of the Nervous Systems (Advances in Experimental Medicine and Biology)
Lowest new price: $47.25
Lowest used price: $27.00
List price: $199.00
Brand: Lubov T Timchenko
World of Unstable Mutations The book "Triplet Repeat Diseases of the Nervous System" overviews the lat est data on several disorders associated with unstable mutations. This field of re search is progressing extremely fast. The number of polymorphic mutations and diseases caused by these mutations is increasing almost every month. There is a strong interest to molecular bases of triplet repeat disorders. This is explained by growing necessity to develop molecular approaches for cure of these diseases. There fore, the authors of this book describe unstable mutations with the emphasis on molecular pathology. Broad discussion is presented on how polymorphic expan sions cause cell dysfunction. o The first chapter of the book focuses on the molecular pathological pro cesses that originate "unstable" mutations. The authors review several avail able models by which normal "stable" region of DNA become pathogenic and discuss possible mechanisms causing DNA instability. o The other chapters of the book describe inherited diseases associated with different types of unstable mutations. Based on the location of mutation in the disease gene, polymorphic expansions of the nervous system can be divided into two major groups. First group includes disorders with unstable expansions within the open reading frame of the gene such as Spinocer ebellar Ataxias caused by polyglutamine expansions. The second group in cludes diseases caused by expansions situated within the untranslated re gions of the gene.
- Triple Repeat Diseases of the Nervous Systems
|Early Detection of Cancer: Molecular Markers
Lowest new price: $32.16
Lowest used price: $7.00
List price: $58.00
Author: Sudhir Srivastava
This text offers a wealth of information regarding early detection. All aspects of molecular marker studies with emphasis on major epithelial cancer sites are presented and several molecular applications for early detection of cancer are described. Identification of defined genetic changes in cells may enable cancer to be detected early enough to increase survival of cancer patients. This text provides the information you need to span the gapy between an understanding of the cancer process and the reduction of cancer morbidity and mortality.
|Molecular Biology of Assemblies and Machines
Lowest new price: $82.10
Lowest used price: $99.56
List price: $158.00
Author: Alasdair Steven
Molecular Biology of Assemblies and Machines presents a comprehensive narrative describing the structures of macromolecular complexes and how they assemble and interact. Richly illustrated, it is written for advanced undergraduates, graduate students, and researchers in biochemistry, structural biology, molecular biology, biophysics, cell biology, and microbiology, and will also appeal to those in chemistry, immunology, and medicine.
Essentially all major biological activities are performed by assemblies of macromolecules (proteins, RNA, and DNA) acting in concert. These assemblies are dynamic and many are endowed with machine-like properties. This unique book explores the molecular mechanisms employed at the critical level between individual macromolecules and cells and organelles.
|Introduction to Protein Structure
Lowest new price: $56.62
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List price: $108.00
Author: Carl Branden
Brand: Brand: Garland Science
Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full-color to illuminate the structural principles described in the text. The first few chapters introduce the general principles of protein structure both for novices and for non-specialists needing a primer. Subsequent chapters use specific examples of proteins to show how they fulfill a wide variety of biological functions. The book ends with chapters on the experimental approach to determining and predicting protein structure, as well as engineering new proteins to modify their functions.
- Used Book in Good Condition
|Fly Pushing: The Theory and Practice of Drosophila Genetics
Lowest new price: $143.26
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List price: $61.00
Author: Ralph J Greenspan
A second edition of the classic handbook has become a standard in the Drosophila field. This edition is expanded to include topics in which classical genetic strategies have been augmented with new molecular tools. Included are such new techniques as homologous recombination, RNAi, new mapping techniques, and new mosaic marking techniques.
|3: Fractals in Biology and Medicine (Mathematics and Biosciences in Interaction)
Lowest new price: $84.10
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List price: $249.00
In March 2000 leading scientists gathered at the Centro Seminariale Monte Verità, Ascona, Switzerland, for the Third International Symposium on "Fractals 2000 in Biology and Medicine". This interdisciplinary conference provided stimulating contributions from the very topical field Fractals in Biology and Medicine. This volume highlights the growing power and efficacy of the fractal geometry in understanding how to analyze living phenomena and complex shapes.
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