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Books

Molecular Biology


Medical Molecular Genetics

Medical Molecular Genetics Lowest new price: $42.37
Lowest used price: $47.46
List price: $32.95
Author: P. A. Hoffee
Brand: Brand: Wiley-Blackwell

Medical Molecular Genetics is one of eight books in the Integrated Medical Sciences (IMS) Series from Fence Creek Publishing. Designed for first- and second-year medical students, they are ideal for use as textbooks, course supplements, or board preparation. The books in the IMS Series focus on the integration of core biomedical concepts and provide insights into the application of basic principles and processes to clinical medicine.

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  • Used Book in Good Condition


Physical Biology: From Atoms to Medicine

Physical Biology: From Atoms to Medicine Lowest new price: $41.93
Lowest used price: $49.38
List price: $48.00
Author: Ahmed Zewail
Brand: Ahmed H Zewail

Edited by Nobel Laureate, Ahmed Zewail, this pioneering book on physical biology includes contributions from four Nobel laureates and other eminent scientists.

This book brings about the confluence of various concepts and tools to address significant problems of our time in physical biology and adjacent disciplines. The volume is structured to provide a broad perspective on current state-of-the-art methods and concepts at the heart of chemical and biological behavior, covering the topics of visualization; theory and computation for complexity; macromolecular function, protein folding, and protein misfolding; molecular recognition; and systems integration from cells to consciousness. The scope of tools is wide-ranging, spanning imaging, crystallography, microfluidics, single-molecule spectroscopy, and synthetic probe targeting, either molecular or by metallic particles. The perspectives are from the point of view of world leaders in physics, chemistry, and biology; and they define potential new frontiers at the interface of these disciplines, including physical, systems, and synthetic biology.

Contents: The Preoccupations of 21st-Century Biology (D Baltimore); Physical Biology: 4D Visualization of Complexity (A H Zewail); The Challenge of Quasi-Regular Structures in Biology (R D Kornberg); The Future of Biological X-ray Analysis (D C Rees); Biology by the Numbers (R Phillips); The Neurobiology of Consciousness (C Koch & F Mormann); Precision Measurements in Biology (S R Quake); Symmetry Breaking, Delocalization and Dynamics in Electron Transfer Systems (N S Hush); and other papers.

Features:

  • Physical Biology From Atoms to Medicine

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Molecular Biology of Assemblies and Machines

Molecular Biology of Assemblies and Machines Lowest new price: $76.91
Lowest used price: $80.40
List price: $158.00
Author: Alasdair Steven

Molecular Biology of Assemblies and Machines presents a comprehensive narrative describing the structures of macromolecular complexes and how they assemble and interact. Richly illustrated, it is written for advanced undergraduates, graduate students, and researchers in biochemistry, structural biology, molecular biology, biophysics, cell biology, and microbiology, and will also appeal to those in chemistry, immunology, and medicine.

Essentially all major biological activities are performed by assemblies of macromolecules (proteins, RNA, and DNA) acting in concert. These assemblies are dynamic and many are endowed with machine-like properties. This unique book explores the molecular mechanisms employed at the critical level between individual macromolecules and cells and organelles.

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Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids

Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids Lowest new price: $42.98
Lowest used price: $26.92
List price: $62.00
Author: Richard Durbin
Brand: Cambridge University Press

Probablistic models are becoming increasingly important in analyzing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analyzing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it is accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time presents the state of the art in this new and important field.

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  • Used Book in Good Condition

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Quantum Field Theory in Strongly Correlated Electronic Systems (Theoretical and Mathematical Physics)

Quantum Field Theory in Strongly Correlated Electronic Systems (Theoretical and Mathematical Physics) Lowest new price: $114.38
Lowest used price: $40.00
List price: $149.00
Author: Naoto Nagaosa
Brand: Naoto Nagaosa

In this book the author extends the concepts introduced in his Quantum Field Theory in Condensed Matter Physics to situations in which the strong electronic correlations are crucial for the understanding of the observed phenomena. Starting from a model field theory to illustrate the basic ideas, more complex systems are analyzed in turn. A special chapter is devoted to the description of antiferromagnets, doped Mott insulators, and quantum Hall liquids from the point of view of gauge theory.

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  • Quantum Field Theory in Strongly Correlated Electronic Systems

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Beginning Perl for Bioinformatics

Beginning Perl for Bioinformatics Lowest new price: $15.94
Lowest used price: $2.25
List price: $39.95
Author: James Tisdall
Brand: Brand: O'Reilly Media

With its highly developed capacity to detect patterns in data, Perl has become one of the most popular languages for biological data analysis. But if you're a biologist with little or no programming experience, starting out in Perl can be a challenge. Many biologists have a difficult time learning how to apply the language to bioinformatics. The most popular Perl programming books are often too theoretical and too focused on computer science for a non-programming biologist who needs to solve very specific problems.Beginning Perl for Bioinformatics is designed to get you quickly over the Perl language barrier by approaching programming as an important new laboratory skill, revealing Perl programs and techniques that are immediately useful in the lab. Each chapter focuses on solving a particular bioinformatics problem or class of problems, starting with the simplest and increasing in complexity as the book progresses. Each chapter includes programming exercises and teaches bioinformatics by showing and modifying programs that deal with various kinds of practical biological problems. By the end of the book you'll have a solid understanding of Perl basics, a collection of programs for such tasks as parsing BLAST and GenBank, and the skills to take on more advanced bioinformatics programming. Some of the later chapters focus in greater detail on specific bioinformatics topics. This book is suitable for use as a classroom textbook, for self-study, and as a reference.The book covers:

  • Programming basics and working with DNA sequences and strings
  • Debugging your code
  • Simulating gene mutations using random number generators
  • Regular expressions and finding motifs in data
  • Arrays, hashes, and relational databases
  • Regular expressions and restriction maps
  • Using Perl to parse PDB records, annotations in GenBank, and BLAST output

Biology, it seems, is a good showcase for the talents of Perl. Newcomers to Perl who understand biological information will find James Tisdall's Beginning Perl for Bioinformatics to be an excellent compendium of examples. Teachers of Perl will likewise find the text to be filled with fresh programming illustrations of growing scientific importance. Seasoned Perlmongers who want to learn biology, however, should search elsewhere, as Tisdall's emphasis is on Perl's logic rather than Mother Nature's.

Departing from O'Reilly's earlier monograph Developing Bioinformatic Computer Skills, Tisdall's text is organized aggressively along didactic lines. Nearly all of the 13 chapters begin with twin bullet lists of Perl programming tools and the bioinformatic methods that require them. Likewise, the chapters end with exercises. String concatenation is illustrated with gene splicing, and regular expressions are taught with gene transcription and motif searching.

Tisdall emphasizes sequence examples throughout, leading up to an introduction to a Perl interface for the NIH GenBank biological database and the widely used BLAST sequence alignment tool. After a brief discussion of three-dimensional protein structure, he returns to sequence extraction and secondary structure prediction.

Tisdall's goal is to boost the beginning programmer into a domain of self-learning. He imparts essential etiquette for the success of programming newbies: use the wealth or resources available, from user documentation to Web site surveys to FAQs to How-To's to news groups and finally to direct personal appeals for help from a senior colleague. A well-plugged-in bioinformatics Perl student will soon discover Bioperl, an open-source effort to bring research-grade bioinformatic tools to the Perl community. Bioperl is described briefly at the end of Tisdall's book and will reportedly be a forthcoming title of its own in the O'Reilly bioinformatics series.

Although he introduces bioinformatics as an academic discipline, Tisdall treats it as a trade throughout his book. He indicates that open questions and computational hard problems exist, but does not describe what they are or how they are being tackled. Ultimately, Tisdall presents bioinformatics as another arrow in a bench scientist's quiver, very much like HPLC, 2D-PAGE, and the various spectroscopies.

As odd as a "bioinformatics-as-tool" book may be to its research proponents, the reduction of bioinformatics to trade status both deflates and vindicates the years of research, as Tisdall's work attests. --Peter Leopold

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  • Used Book in Good Condition

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Fly Pushing: The Theory and Practice of Drosophila Genetics

Fly Pushing: The Theory and Practice of Drosophila Genetics Lowest new price: $40.00
Lowest used price: $90.22
List price: $61.00
Author: Ralph J Greenspan

A second edition of the classic handbook has become a standard in the Drosophila field. This edition is expanded to include topics in which classical genetic strategies have been augmented with new molecular tools. Included are such new techniques as homologous recombination, RNAi, new mapping techniques, and new mosaic marking techniques.

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Methods for Investigation of Amino Acid and Protein Metabolism (Methods in Nutritional Research)

Methods for Investigation of Amino Acid and Protein Metabolism (Methods in Nutritional Research) Lowest new price: $19.32
Lowest used price: $3.93
List price: $231.00
Brand: Antoine E El Khoury

Containing all the new as well as classical methodologies used in the investigation of amino acid and protein metabolism in human and animal models, this book is needed because of the dramatic increase in research in this field. There is no other book currently on the market that covers these methods of investigation.
Methods for Investigation of Amino Acid and Protein Metabolism explores areas such as amino acid transfer across tissue membranes, past and new applications using stable isotopes, protein synthesis in organs and tissues, and more. Because of the importance of research methods in the field of amino acid and protein nutrition and metabolism, this book facilitates the reader's integration of the concepts involved in these investigative research methods and their corollaries.
In addition to helping any nutrition investigator design and conduct appropriate research protocols in this area of nutrition, this book assists students who are planning to investigate amino acid and protein metabolism in humans or laboratory animals.

Features:

  • Methods for Investigation of Amino Acid and Protein Metabolism


An Introduction to Molecular Medicine and Gene Therapy

An Introduction to Molecular Medicine and Gene Therapy Lowest new price: $48.25
Lowest used price: $2.48
List price: $146.95

Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies.

In addition, An Introduction to Molecular Medicine and Gene Therapy:

  • Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations
  • Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases
  • Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter
  • Contains appendices on commercial implications and a review of the history of gene therapy

This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.


Virus Taxonomy: Seventh Report of the International Committee on Taxonomy of Viruses

Virus Taxonomy: Seventh Report of the International Committee on Taxonomy of Viruses Lowest new price: $254.67
Lowest used price: $33.48
List price: $185.95

Universal, unambiguous virus taxonomy (naming and categorization) is vital for distinguishing the thousands of viruses which have been isolated from humans, animals, plants, fungi, bacteria, and archae. Before an official identification and classification system was devised, there was much confusion and duplication of viruses isolated in different labs around the world. The first internationally organized attempts to introduce some order in the bewildering variety of viruses took place at the International Congress of Microbiology held in Moscow in 1966. A committee, later called The International Committee on Taxonomy of Viruses (ICTV), was given the task of developing a single, universal taxonomic scheme for all the viruses.
This is the seventh report produced by the ICTV and builds on the accumulated taxonomic data of its predecessors and records the proceedings of the Committee since 1995, including decisions reached at the Tenth International Congress of Virology held in Jerusalem in 1996, and at mid-term meetings in 1997 and 1998. The information is essential for anyone working in the field of virology. Clinicians in diagnostic laboratories, researchers citing viruses in published papers, and virologists in the business industry all must have the most updated virus taxonomy to make the appropriate references. The number of recognized viruses continues to grow with the development of better detection techniques, and the rapid evolution of virus variants.

Key Features
* The official reference for virus taxonomy and nomenclature
* Contains 30% new taxa, including two major new contributions on the phylogenetic relationships between viruses, and application of the virus species concept throughout the virus world
* Compiles information from 300-400 experts
* Covers over 4000 recognized viruses, organized by family, with diagrams of genome organization and virus replication cycle where know
* Includes over 300 figures and illustrations


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