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Molecular Biology


Molecular Biotechnology: Principles and Applications of Recombinant DNA

Molecular Biotechnology: Principles and Applications of Recombinant DNA Lowest new price: $9.55
Lowest used price: $1.99
List price: $42.95
Author: Bernard R. Glick

This textbook covers both the scientific principles and industrial applications of recombinant DNA technology. Molecular biotechnology is a relatively new discipline that uses recombinant DNA technology for the development of commercial products. The book explains the principles of recombinant DNA technology as well as other important ancillary techniques such as DNA sequencing, the polymerase chain reaction and the production of monoclonal antibodies. It describes the experimental approaches for each area of molecular biotechnology and provides an understanding of what the studies entail, how they are being carried out, why they are important and, where important, the social aspects of molecular biotechnology.

Features:

  • MOLECULAR BIOTECHNOLOGY - TEXT TO COVER UNDERLYING SCIENTIFIC PRINCIPLES AND INDUSTRIAL, AGRICULTURAL, PHARMACEUTICAL AND BIOMEDICALAPPLICATIONS


Transcription Factors in the Nervous System: Development, Brain Function, and Diseases

Transcription Factors in the Nervous System: Development, Brain Function, and Diseases Lowest new price: $49.98
Lowest used price: $19.02
List price: $260.00

This first book to cover neural development, neuronal survival and function on the genetic level outlines promising approaches for novel therapeutic strategies in fighting neurodegenerative disorders, such as Alzheimer's disease. Focusing on transcription factors, the text is clearly divided into three sections devoted to transcriptional control of neural development, brain function and transcriptional dysregulation induced neurological diseases.
With a chapter written by Nobel laureate Eric Kandel, this is essential reading for neurobiologists, geneticists, biochemists, cell biologists, neurochemists and molecular biologists.


Human Blood Groups: Chemical and Biochemical Basis of Antigen Specificity

Human Blood Groups: Chemical and Biochemical Basis of Antigen Specificity Lowest new price: $116.50
Lowest used price: $67.61
List price: $339.00
Author: Helmut Schenkel-Brunner
Brand: Brand: Springer

This monograph covers the entire field of blood group serology, with its main emphasis on the chemical and biochemical basis of blood group specificity. Full consideration is given to molecular biology investigations, in particular to studies on the structure of blood group genes and the molecular biological basis of alleles and rare blood group variants, whereby relevant literature up to the year 2000 is covered. The text is supplemented by numerous illustrations and tables, and detailed reference lists.

Features:

  • Used Book in Good Condition


Morphometrics For The Life Sciences

Morphometrics For The Life Sciences Lowest new price: $68.99
Lowest used price: $31.00
List price: $69.00
Author: Pete E. Lestrel
Brand: Brand: World Scientific Pub Co Inc

The idea of form is one of the most fundamental concepts underlying all of the sciences. Our visual system is so well developed that we are able to effortlessly classify and compare visual images. What is not so well developed has been our ability to measure this visual information. This book examines a number of recent approaches currently in use to numerically characterize the biological form. It presents a unique overview of these methods, starting with a review of measurement set in a historical framework. The book will be of interest to graduate students in addition to a wide range of researchers, including those in the specialized fields of human biology, growth and development, orthodontics, botany, biology, ecology, zoology, as well as dentistry and medicine.

Features:

  • Used Book in Good Condition


Molecular Dissection of Complex Traits

Molecular Dissection of Complex Traits Lowest new price: $47.83
Lowest used price: $21.50
List price: $275.00
Author: Andrew H. Paterson
Brand: Brand: CRC Press

In the past 10 years, contemporary geneticists using new molecular tools have been able to resolve complex traits into individual genetic components and describe each such component in detail. Molecular Dissection of Complex Traits summarizes the state of the art in molecular analysis of complex traits (QTL mapping), placing new developments in this field within the context of their historical origins. Leading authorities address central themes in analysis of complex phenotypes, and case histories of important work in this burgeoning field are presented by the principal investigators.
The book is divided into three sections:

Features:

  • Used Book in Good Condition


Quantum Field Theory in Strongly Correlated Electronic Systems (Theoretical and Mathematical Physics)

Quantum Field Theory in Strongly Correlated Electronic Systems (Theoretical and Mathematical Physics) Lowest new price: $113.50
Lowest used price: $40.00
List price: $149.00
Author: Naoto Nagaosa
Brand: Naoto Nagaosa

In this book the author extends the concepts introduced in his Quantum Field Theory in Condensed Matter Physics to situations in which the strong electronic correlations are crucial for the understanding of the observed phenomena. Starting from a model field theory to illustrate the basic ideas, more complex systems are analyzed in turn. A special chapter is devoted to the description of antiferromagnets, doped Mott insulators, and quantum Hall liquids from the point of view of gauge theory.

Features:

  • Quantum Field Theory in Strongly Correlated Electronic Systems

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Essential Cell Biology: An Introduction to the Molecular Biology of the Cell

Essential Cell Biology: An Introduction to the Molecular Biology of the Cell Lowest new price: $18.98
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List price: $134.00
Author: Bruce Alberts
Brand: Brand: Garland

An introduction to cell biology. This book contains a range of pedagogic features including Q&As and artwork.

Features:

  • Used Book in Good Condition

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Genes and Signals

Genes and Signals Lowest new price: $35.35
Lowest used price: $15.85
List price: $39.00
Author: Mark Ptashne and Alexander Gann
Brand: Brand: Cold Spring Harbor Laboratory Press

Genes & Signals analyzes gene regulation from a new perspective. The first chapter describes mechanisms found in bacteria, and two subsequent chapters discuss which of these is most highly exploited in higher organisms. A final chapter relates these molecular strategies to other enzymatic processes, including those involving kinases, RNA splicing enzymes, proteases, and others. A general theme emerges, one that proposes how a rather restricted set of signals and enzymatic functions has been used in evolution to generate complex life forms of different types.

Features:

  • Used Book in Good Condition

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Gene Quantification (Advanced Biomedical Technologies)

Gene Quantification (Advanced Biomedical Technologies) Lowest new price: $49.89
Lowest used price: $15.95
List price: $319.00
Brand: Edwin M Southern

Geneticists and molecular biologists have been interested in quantifying genes and their products for many years and for various reasons (Bishop, 1974). Early molecular methods were based on molecular hybridization, and were devised shortly after Marmur and Doty (1961) first showed that denaturation of the double helix could be reversed - that the process of molecular reassociation was exquisitely sequence dependent. Gillespie and Spiegelman (1965) developed a way of using the method to titrate the number of copies of a probe within a target sequence in which the target sequence was fixed to a membrane support prior to hybridization with the probe - typically a RNA. Thus, this was a precursor to many of the methods still in use, and indeed under development, today. Early examples of the application of these methods included the measurement of the copy numbers in gene families such as the ribosomal genes and the immunoglo­ bulin family. Amplification of genes in tumors and in response to drug treatment was discovered by this method. In the same period, methods were invented for estimating gene num­ bers based on the kinetics of the reassociation process - the so-called Cot analysis. This method, which exploits the dependence of the rate of reassociation on the concentration of the two strands, revealed the presence of repeated sequences in the DNA of higher eukaryotes (Britten and Kohne, 1968). An adaptation to RNA, Rot analysis (Melli and Bishop, 1969), was used to measure the abundance of RNAs in a mixed population.

Features:

  • Gene quantification


Moving Questions: A History of Membrane Transport and Bioenergetics

Moving Questions: A History of Membrane Transport and Bioenergetics Lowest new price: $55.88
Lowest used price: $13.00
List price: $95.00
Author: Joseph D. Robinson

This book describes half a century of progress in two mainstream areas of biological research: membrane transport, initially a focus of physiologists, and oxidative phosphorylation, initially a focus of biochemists. Robinson shows how the development of new explanatory models had unexpectedly merged these inquiries into a new field, bioenergetics. In the late 1930s, explanations for the asymmetric distribution of ions between cells and their environments invoked absolute impermeabilities of the cell's surrounding membranes. But new experiments contradicted that idea and demonstrated that forming the transmembrane distributions required metabolic energy, implying the participation of active transport "pumps." Subsequent studies identified, isolated, and characterized these pumps as enzymes coupling ionic transport to the consumption of adenosine triphosphate (ATP), an "energy-rich" molecule serving as a cellular energy store. In the late 1930s oxidative phosphylation, the process of coupling ATP synthesis to oxidative metabolism, was identified. The explanatory model emerging in the next decades, however, did not follow the enzymatic precedents of known metabolic phosphorylations but rather embodied the principle that metabolic oxidations drive active transport pumps to create transmembrane distribution of ions, with these ionic asymmetries then driving ATP synthesis. It was discovered that ATP consumption can form ionic asymmetries; ionic asymmetries can drive ATP formation; and ionic asymmetries-like ATP-can also power other cellular functions.


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