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Molecular Biology


Principles of Genome Analysis and Genomics

Principles of Genome Analysis and Genomics Lowest new price: $29.50
Lowest used price: $3.00
List price: $117.95
Author: Sandy B. Primrose
Brand: Brand: Wiley-Blackwell

With the first draft of the human genome project in the publicdomain and full analyses of model genomes now available, thesubject matter of 'Principles of Genome Analysis and Genomics' iseven 'hotter' now than when the first two editions were publishedin 1995 and 1998. In the new edition of this very practical guideto the different techniques and theory behind genomes and genomeanalysis, Sandy Primrose and new author Richard Twyman provide afresh look at this topic. In the light of recent excitingadvancements in the field, the authors have completely revised andrewritten many parts of the new edition with the addition of fivenew chapters. Aimed at upper level students, it is essential thatin this extremely fast moving topic area the text is up to date andrelevant.


  • Completely revised new edition of an establishedtextbook.
  • Features new chapters and examples from exciting new researchin genomics, including the human genome project.
  • Excellent new co-author in Richard Twyman, also co-author ofthe new edition of hugely popular Principles of GeneManipulation.
  • Accompanying web-page to help students deal with this difficulttopic at www.blackwellpublishing.com/primrose

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Essential Cell Biology: An Introduction to the Molecular Biology of the Cell

Essential Cell Biology: An Introduction to the Molecular Biology of the Cell Lowest new price: $19.00
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List price: $134.00
Author: Bruce Alberts
Brand: Brand: Garland

Explains the basics of cell biology for people with a minimal knowledge of biology

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An Electronic Companion to Molecular Cell Biology¿

An Electronic Companion to Molecular Cell Biology¿ Lowest new price: $4.44
Lowest used price: $4.44
List price: $49.95
Author: Robert G. Van Buskirk
Brand: Brand: Cogito

This is a dynamic alternative to conventional study guides. Developed by a prominent educator and researcher, this will complement most Molecular Cell Biology texts.

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Marijuana and Cannabinoid Research: Methods and Protocols (Methods in Molecular Medicine)

Marijuana and Cannabinoid Research: Methods and Protocols (Methods in Molecular Medicine) Lowest new price: $46.62
Lowest used price: $28.67
List price: $189.00
Brand: Brand: Humana Press

A cutting-edge collection of readily reproducible in vitro and in vivo methods to elucidate the mechanisms associated with cannabinoid function in health and disease. The techniques can be used in studies across the board from genes to behavior. The molecular neurobiological methods are invaluable in analyzing the structure, the polymorphisms, and the molecular expression of the cannabinoid receptors (CBrs), as well as their association with polysubstance abuse. There are also methods for localizing cannabinoid receptors in different systems, visualizing cannabinoid effects using brain slice imaging and elctrophysiological approaches, and designing and synthesizing cannabinoids and endocannabinoids. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

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An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases

An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases Lowest new price: $22.91
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List price: $154.95
Author: Jack J. Pasternak

An Introduction to Human Molecular Genetics
Second Edition
Jack J. Pasternak
The Second Edition of this internationally acclaimed text expandsits coverage of the molecular genetics of inherited human diseaseswith the latest research findings and discoveries. Using a unique,systems-based approach, the text offers readers a thoroughexplanation of the gene discovery process and how defective genesare linked to inherited disease states in major organ and tissuesystems. All the latest developments in functional genomics,proteomics, and microarray technology have been thoroughlyincorporated into the text.
The first part of the text introduces readers to the fundamentalsof cytogenetics and Mendelian genetics. Next, techniques andstrategies for gene manipulation, mapping, and isolation areexamined. Readers will particularly appreciate the text'sexceptionally thorough and clear explanation of genetic mapping.The final part features unique coverage of the molecular geneticsof distinct biological systems, covering muscle, neurological, eye,cancer, and mitochondrial disorders. Throughout the text, helpfulfigures and diagrams illustrate and clarify complex material.
Readers familiar with the first edition will recognize the text'ssame lucid and engaging style, and will find a wealth of new andexpanded material that brings them fully up to date with a currentunderstanding of the field, including:
* New chapters on complex genetic disorders, genomic imprinting,and human population genetics
* Expanded and fully revised section on clinical genetics, coveringdiagnostic testing, molecular screening, and varioustreatments
This text is targeted at upper-level undergraduate students,graduate students, and medical students. It is also an excellentreference for researchers and physicians who need a clinicallyrelevant reference for the molecular genetics of inherited humandiseases.


Translational Control of Gene Expression (Cold Spring Harbor Monograph)

Translational Control of Gene Expression (Cold Spring Harbor Monograph) Lowest new price: $134.53
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Author: Nahum Sonberg
Brand: Brand: Cold Spring Harbor Laboratory Press

Since the 1996 publication of Translational Control, there has been fresh interest in protein synthesis and recognition of the key role of translational control mechanisms in regulating gene expression. This new monograph updates and expands the scope of the earlier book but it also takes a fresh look at the field. In a new format, the first eight chapters provide broad overviews, while each of the additional twenty-eight has a focus on a research topic of more specific interest. The result is a thoroughly up-to-date account of initiation, elongation, and termination of translation, control mechanisms in development in response to extracellular stimuli, and the effects on the translational machinery of virus infection and disease. This book is essential reading for students entering the field and an invaluable resource for investigators of gene expression and its control.

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The Nematode Caenorhabditis elegans (The Cold Spring Harbor Monograph Series)

The Nematode Caenorhabditis elegans (The Cold Spring Harbor Monograph Series) Lowest new price: $50.00
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Brand: Brand: Cold Spring Harbor Laboratory Press

In 1965 Sydney Brenner chose the free-living nematode Caenorhabditis elegans as a promising model system for a concerted genetic, ultrastructural, and behavioral attack on the development and function of a simple nervous system. Since then, with the help of a growing number of investigators, knowledge about the biology of "the worm" has accumulated at a steadily accelerating pace to the extent that C. elegans is now probably the most completely understood metazoan in terms of anatomy, genetics, development, and behavior. The past few years have seen the completion of two major long-term projects that provide new insights into C. elegans development and lay important groundwork for future investigation: completion of the cell lineages of both sexes, from zygote to adult, and description of the complete anatomy at the level of electron microscope resolution, providing a complete "wiring diagram" of cell contacts in the animal. Recent years have also brought the first successes in molecularly cloning genes of developmental interest defined only by mutation, using transposon tagging as a generally applicable method for identification of the desired DNA sequences. Reintroduction of cloned DNA sequences into the genome has recently been accomplished. A physical map of the genome has been assembled with a combination of cosmid and YAC genes. This "Book of the Worm" serves as a reference source for C. elegans investigators as well as an introductory monograph for other biologists.

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Introduction to Biotechnology

Introduction to Biotechnology Lowest new price: $16.00
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List price: $105.40
Author: William J. Thieman
Brand: Brand: Benjamin Cummings

Introduction to Biotechnology is the first biotechnology textbook geared specifically for the diverse scientific backgrounds of undergraduate students interested in pursuing a career in biotechnology. With its balanced coverage of basic molecular biology, historical developments, and contemporary applications, the text provides you with the tools and basic knowledge for success in the biotech industry. Author William Thieman chairs one of the leading biotech programs in California (Ventura College), and co-author Michael A. Palladino is a molecular biologist with considerable expertise in directing undergraduate student research in recombinant DNA technology. A comprehensive introduction, including sections on genes & genomes, recombinant DNA technology, forensic analysis, and a variety of biotechnology types such as agricultural and medical. For college instructors, students, or anyone interested in biotechnology.

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Platelets and Megakaryocytes: Volume 1: Functional Assays (Methods in Molecular Biology)

Platelets and Megakaryocytes: Volume 1: Functional Assays (Methods in Molecular Biology) Lowest new price: $46.62
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List price: $199.99
Brand: Brand: Humana Press

12 The average human body has in the order of 10 circulating platelets. They are crucial for hemostasis, and yet excessive platelet activation is a major cause of m- bidity and mortality in western societies. It is therefore not surprising that platelets have become one of the most extensively investigated biological cell types. We are, however, far from understanding precisely how platelets become activated under physiological and pathophysiological conditions. In addition, there are large gaps in our knowledge of platelet production from their giant precursor cell, the megakar- cyte. Understanding megakaryocyte biology will be crucial for the development of platelet gene targeting. The aim of Platelets and Megakaryocytes is therefore to bring together established and recently developed techniques to provide a comprehensive guide to the study of both the platelet and the megakaryocyte. It consists of five s- tions split between two volumes. The more functional assays appear in Volume 1, whereas Volume 2 includes signaling techniques, postgenomic methods, and a n- ber of key perspectives chapters. Part I of Volume 1, Platelets and Megakaryocytes: Functional Assays, describes many well established approaches to the study of platelet function, including aggregometry, secretion, arachidonic acid metabolism, procoagulant responses, pla- let adhesion under static or flow conditions, flow cytometry, and production of microparticles. Although one would ideally wish to perform experiments with human platelets, studies within the circulation using intravital microscopy require the use of animal models, which are described in Chapter 16, vol. 1.

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Spectroscopic Data of Saponins: The Triterpenoid Glycosides, 3-Volume Set

Spectroscopic Data of Saponins: The Triterpenoid Glycosides, 3-Volume Set Lowest new price: $58.44
Lowest used price: $29.99
List price: $2,314.00
Author: Viqar Uddin Ahmad

Spectroscopic Data of Saponins: The Triterpenoid Glycosides contains the physical and spectroscopic data of over 2,600 triterpene glycosides, along with occurrence and biological activities. It offers a wealth of information, such as chemical structure, biological source with family, molecular weight, melting point, and optical rotation with solvent. The text features computer-generated illustrations that clearly indicate the stereochemistry at different points, along with the glycosidic linkages. It furnishes four indices - compound index, plant source index, registry number index, and molecular formula index - that make it easy to locate particular compounds within the book.


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